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. 2021 Apr 28;592(7856):747–755. doi: 10.1038/s41586-020-03040-7

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© The Author(s), under exclusive licence to Springer Nature Limited 2021

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Fig. 1 — a, Phylogenetic distribution of OT, VT and OTR-VTR genes among vertebrates. Filled circles, presence of a gene; empty circles, loss of a gene; no circle, the gene never evolved in that lineage. Phylogenetic tree based on ref. ³⁶. *Unresolved relationship for whether hagfishes and lampreys constitute a single phylum or two separate phyla^35,37. b, Local chromosomal organization of the OT and VT region. Representation of the position (in kb), orientation (+ or −) of OT and VT genes (exons + introns) in human chromosome 12, intron length (scale, 100 bases), GC content and DNA transposable elements with terminal inverted repeats (TE-TIRs) (green).