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. 2021 Apr 15;8:630802. doi: 10.3389/fmed.2021.630802

Table 2.

Comparison of initial laboratory findings between FC and NF groups.

Parameters Total
(n = 178)
FC group
(n = 108)
NF group
(n = 70)
p-value
WBC count (normal range, 4.0–9.5 × 109/L) 5.35 ± 2.60 5.13 ± 2.89 5.68 ± 2.05 0.163
  <4 53/178 (29.8) 37/108 (34.3) 16/70 (22.9) 0.261
 4–10 118/178 (66.3) 67/108 (62.0) 51/70 (72.9)
 >10 7/178 (3.9) 4/108 (3.7) 3/70 (4.3)
Neutrophil count (normal range, 1.8–6.3 × 109/L) 3.33 ± 2.26 3.22 ± 2.57 3.53 ± 1.58 0.395
 >6.3 10/170 (5.9) 6/108 (5.6) 4/62 (6.5) 1.000
Lymphocyte count (normal range, 1.1–3.2 × 109/L) 1.52 ± 2.05 1.20 ± 0.51 2.00 ± 3.15 0.044*
  <1.1 74/172 (43.0) 57/104 (54.8) 17/68 (25.0) <0.001*
C-reactive protein (normal range, ≤ 6 mg/L) 12.27 ± 22.68 12.74 ± 22.87 11.50 ± 22.52 0.730
 >10 40/171 (23.4) 27/107 (25.2) 13/64 (20.3) 0.462
ALT (normal range, 9–50 U/L) 24.47 ± 23.63 22.26 ± 14.91 28.45 ± 33.95 0.184
 >50 14/168 (8.3) 6/108 (5.6) 8/60 (13.3) 0.081
AST (normal range, 15–40 U/ L) 26.10 ± 15.27 24.81 ± 11.22 28.33 ± 20.42 0.213
 >40 18/170 (10.6) 8/108 (7.4) 10/62 (16.1) 0.075
LDH (normal range, 120–250 U/L) 194.21 ± 80.91 190.78 ± 56.35 198.12 ± 102.75 0.704
 >250 13/77 (16.9) 6/41 (14.6) 7/36 (19.4) 0.574
D-dimer (normal range, 0–0.5 mg/L) 0.44 ± 1.59 0.44 ± 1.93 0.43 ± 0.68 0.962
 >0.5 22/170 (12.9) 12/108 (11.1) 10/62 (16.1) 0.348
Procalcitonin (normal range, 0–0.1 ng/mL) 0.20 ± 0.48 0.22 ± 0.60 0.16 ± 0.12 0.475
 >0.5 6/170 (3.5) 4/108 (3.7) 2/62 (3.2) 1.000

Data were expressed as mean ± SD or n (%); FC, familial cluster; NF, non-familial; SD, standard deviation; WBC, white blood cell; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactose dehydrogenase;

*

p < 0.05, comparison between FC and NF groups.