Table 3.
Comparison of CT features at different time points between FC and NF groups.
| On-admission | End-hospitalization | |||||||
|---|---|---|---|---|---|---|---|---|
|
Total (n = 147) |
FC group (n = 87) |
NF group (n = 60) |
p-value |
Total (n = 127) |
FC group (n = 71) |
NF group (n = 56) |
p-value | |
| Sum severity CT scores | 3.5 ± 3.1 | 3.9 ± 3.2 | 3.0 ± 2.9 | 0.059 | 3.8 ± 3.8 | 4.6 ± 3.1 | 2.7 ± 4.2 | 0.005* |
| Predominant CT pattern | 0.226 | <0.001* | ||||||
| Normal | 28 (19.0) | 14 (16.1) | 14 (23.3) | 27 (21.3) | 4 (5.6) | 23 (41.1)* | ||
| GGO | 77 (52.4) | 52 (59.8) | 25 (41.7) | 48 (37.8) | 29 (40.8) | 19 (33.9) | ||
| Consolidation | 14 (9.5) | 7 (8.0) | 7 (11.7) | 9 (7.1) | 7 (9.9) | 2 (3.6) | ||
| Mixed pattern | 22 (15.0) | 12 (13.8) | 10 (16.7) | 7 (5.5) | 4 (5.6) | 3 (5.4) | ||
| Linear opacities | 6 (4.1) | 2 (2.3) | 4 (6.7) | 36 (28.3) | 27 (38.0) | 9 (16.1)* | ||
| Number of involved lobes | 2.7 ± 1.9 | 3.0 ± 1.9 | 2.3 ± 1.9 | 0.017* | 2.8 ± 2.0 | 3.6 ± 1.6 | 1.7 ± 1.9 | <0.001* |
| 0.156 | <0.001* | |||||||
| 0 | 28 (19.0) | 14 (16.1) | 14 (23.3) | 27 (21.3) | 4 (5.6) | 23 (41.1)* | ||
| 1 | 22 (15.0) | 9 (10.3) | 13 (21.7) | 17 (13.4) | 6 (8.5) | 11 (19.6) | ||
| 2 | 19 (12.9) | 11 (12.6) | 8 (13.3) | 13 (10.2) | 7 (9.9) | 6 (10.7) | ||
| 3 | 16 (10.9) | 9 (10.3) | 7 (11.7) | 12 (9.4) | 9 (12.7) | 3 (5.4) | ||
| 4 | 21 (14.3) | 16 (18.4) | 5 (8.3) | 16 (12.6) | 13 (18.3) | 3 (5.4) | ||
| 5 | 41 (27.9) | 28 (32.2) | 13 (21.7) | 42 (33.1) | 32 (45.1) | 10 (17.9)* | ||
| Other CT findings | ||||||||
| Pleural effusion | 5 (3.4) | 4 (4.6) | 1 (1.7) | 0.649 | 5 (3.9) | 4 (5.6) | 1 (1.8) | 0.383 |
| Lymphadenopathy | 11 (7.5) | 9 (10.3) | 2 (3.3) | 0.200 | 8 (6.3) | 7 (9.9) | 1 (1.8) | 0.077 |
| Air bronchogram | 27 (18.4) | 17 (19.5) | 10 (16.7) | 0.658 | 0 (0) | 0 (0) | 0 (0) | / |
| Enlarged vessels | 30 (20.4) | 14 (16.1) | 16 (26.7) | 0.118 | 5 (3.9) | 4 (5.6) | 1 (1.8) | 0.383 |
| Pleural thickening | 38 (25.9) | 21 (24.1) | 17 (28.3) | 0.568 | 25 (19.7) | 16 (22.5) | 9 (16.1) | 0.363 |
| Distribution of lesions | 0.222 | <0.001* | ||||||
| Peripheral | 96 (65.3) | 57 (65.5) | 39 (65.0) | 71 (55.9) | 47 (66.2) | 24 (42.9)* | ||
| Random | 18 (12.2) | 11 (12.6) | 7 (11.7) | 14 (11.0) | 11 (15.5) | 3 (5.4) | ||
| Diffuse | 5 (3.4) | 5 (5.7) | 0 (0) | 15 (11.8) | 9 (12.7) | 6 (10.7) | ||
| Normal | 28 (19.0) | 14 (16.1) | 14 (23.3) | 27 (21.3) | 4 (5.6) | 23 (41.1)* | ||
Data were expressed as mean ± SD or n (%); FC, familial cluster; NF, non-familial; GGO, ground-glass opacities; SD, standard deviation.
*
p < 0.05, comparison between FC and NF groups.