Table 1.
Author | No. of patients | Efficacy | Safety |
---|---|---|---|
Abolghasemi | 189 | No differences in mortality. Lower length of hospitalization and higher discharges. | No adverse events |
Cheng | 80 | Better clinical outcomes with early plasma administration | No adverse reactions |
Gharbharan* | 86 | No improvement in mortality, hospital stay, or day-15 disease severity | No serious adverse events |
Joyner | 21987 | Decrease in mortality rate | Adverse events in less than 1% (transfusion reactions, thrombotic events, cardiac events). |
Li* | 103 | No improvement in clinical within 28 days | 2 patients had an adverse event after transfusion that improved with supportive therapy |
Xia | 138 | Symptoms improvement and lower mortality rate | No serious adverse events |
*Randomized clinical trials. Dpt, Days post-transfusion.