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. 2021 Apr 15;12:633184. doi: 10.3389/fimmu.2021.633184

Table 1.

Efficacy and safety of convalescent plasma transfusion as a treatment for COVID-19 patients.

Author No. of patients Efficacy Safety
Abolghasemi 189 No differences in mortality. Lower length of hospitalization and higher discharges. No adverse events
Cheng 80 Better clinical outcomes with early plasma administration No adverse reactions
Gharbharan* 86 No improvement in mortality, hospital stay, or day-15 disease severity No serious adverse events
Joyner 21987 Decrease in mortality rate Adverse events in less than 1% (transfusion reactions, thrombotic events, cardiac events).
Li* 103 No improvement in clinical within 28 days 2 patients had an adverse event after transfusion that improved with supportive therapy
Xia 138 Symptoms improvement and lower mortality rate No serious adverse events

*Randomized clinical trials. Dpt, Days post-transfusion.