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. 2021 Feb 2;12(1):99–117. doi: 10.1016/j.jcmgh.2021.01.020

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Gene signatures found in the inflamed samples (UC) compared with noninflamed samples (SC) and healthy samples (HCs) in epithelial/stromal cells. Enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) pathways of DEGs between (A) UC vs HCs and (B) UC vs SC. (C) Heatmaps showing the expression changes (UC vs HCs) of detected genes in IL-17 signaling and allograft rejection pathway in each Epithelial/stromal cell cluster. (D) Violin plots showing the expression distribution of LCN2 and MHC class II genes in each epithelial and stromal cell cluster of UC, SC, and HCs.