Table 3. Demographics and clinical features between two groups of benign LM and subungual melanoma.
| Variable | Total patients (n=68) | Benign LM (n=60) | Subungual melanoma (n=8) | p-value |
|---|---|---|---|---|
| Age (yr) | 35.2±20.1 | 33.5±19.6 | 48.5±20.4 | 0.035 |
| Duration of LM (mo) | 42.8±64.9 | 27.6±41.8 | 141.0±99.6 | 0.004 |
| Location of LM | ||||
| Hand or foot | 0.184 | |||
| Hand | 53 (77.9) | 45 (75.0) | 8 (100) | |
| Foot | 15 (22.1) | 15 (25.0) | 0 (0) | |
| Right or left | 0.135 | |||
| Right | 32 (47.1) | 26 (43.3) | 6 (75.0) | |
| Left | 36 (52.9) | 34 (56.7) | 2 (25.0) | |
| Width of LM (ratio) | 0.21±0.17 | 0.17±0.12 | 0.49±0.26 | <0.001 |
| Color of LM | 0.022 | |||
| Monochromic | 36 (52.9) | 35 (58.3) | 1 (12.5) | |
| Heterochromic | 32 (47.1) | 25 (41.7) | 7 (87.5) | |
| Hutchinson sign | 16 (23.5) | 12 (20.0) | 4 (50.0) | 0.062 |
| Border of LM | 0.700 | |||
| Well defined | 43 (63.2) | 37 (61.7) | 6 (75.0) | |
| Blurred | 25 (36.8) | 23 (38.3) | 2 (25.0) | |
| Nail plate dystrophy | 15 (22.1) | 10 (16.7) | 5 (62.5) | 0.010 |
| Longitudinal ridge | 12 | 8 | 4 | |
| Split of nail plate | 1 | 0 | 1 | |
| Nail plate dystrophy | 1 | 1 | 0 | |
| Horizontal groove | 1 | 1 | 0 | |
| Recent change of LM* | 21 (30.9) | 16 (26.7) | 5 (62.5) | 0.096 |
| Change of color | 12 | 11 | 1 | |
| Change of width | 11 | 7 | 4 | |
| Change of length | 1 | 0 | 1 |
Values are presented as mean±standard deviation, number (%), or number only. LM: longitudinal melanonychia. *The detailed symptoms appeared independently or in combination, the number of ‘recent change of LM’ and the number of detailed symptoms can be different.