Table 4.

Total in vitro synergy scores between carfilzomib and conventional chemotherapy agents.

Cell Line	Vincristine	Daunorubicin	Dexamethasone	Cytarabine	Methotrexate	6-Mercaptopurine	L-Asparaginase	6-Thioguanine	4-HPC
PER-494	36.07	170.57	41.98	−24.52	−41.30	9.30	56.93	−48.40	59.60
PER-485	86.40	282.00	39.02	593.00	200.00	−211.30	320.33	36.83	386.33
PER-490	18.93	98.90	38.90	81.22	−54.10	37.77	247.67	156.10	235.00
PER-784	−192.00	−59.77	−138.00	−199.33	−302.00	−320.33	151.00	−54.16	−12.30
PER-826	162.10	71.20	196.50	68.40	−59.67	2.80	383.00	69.95	177.50
PER-785	197.67	240.00	188.00	−72.37	−52.53	−12.94	99.15	5.40	161.17
PER-703	83.00	275.00	−223.43	661.00	53.33	−311.37	−344.67	262.67	−185.07
PER-910	−6.34	269.50	240.33	23.73	−285.67	−159.50	192.00	−164.00	84.60
Colour key:
<−100	Antagonism
0 to −100	Mild antagonism
0 to 100	Additive
100 to 200	Mild synergy
200 to 300	Synergy
>300	Strong synergy