Table 2.

Spirometry Measurements Including Mean Forced Expiratory Volume in One Second, Forced Vital Capacity, and Forced Expiratory Flow at 25–75% Values, Percent Predicted, and z-Scores During Hospitalization (Initial) and During Outpatient Follow-Up

Case	Days to FU	FVC (L)	FVC (%)	FVC (z)	FEV1 (L)	FEV1 (%)	FEV1 (z)	FEV1/FVC (%)	FEF 25–75 (L)	FEF 25–75 (%)	FEF 25–75 (z)	DLCO
1
Initial	31	2.01	53.7	−3.98	1.76	53.0	−3.87	87	2.03	53.5	−2.49	75.2
FU		3.19	85.1	−1.23	2.82	84.8	−1.29	88	3.22	84.8	−0.90	69.1
2
Initial	29	4.45	84.6	−1.34	3.71	82.5	−1.48	83	3.73	75.8	−1.13	76.9
FU		5.24	99.4	−0.05	4.03	89.4	−0.90	77	3.36	68.1	−1.53	N/A
3
Initial	27	3.37	60.5	−3.47	3.04	64.2	−2.94	90	4.58	90.2	−0.44	77.4
FU		5.59	99.8	0.70	5.03	105.5	0.47	90	6.72	131.4	1.29	N/A
4
Initial	43	4.03	77.5	−1.97	3.35	75.4	−2.11	83	3.91	79.8	−0.92	N/A
FU		5.81	111.5	0.99	4.50	113.1	1.15	77	3.88	79.1	−0.96	71.4
5
Initial	26	2.30	74.4	−2.27	1.82	64.9	−2.89	79	1.70	48.6	−2.62	N/A
FU		3.26	105.1	0.44	3.03	107.7	0.66	93	4.24	120.9	0.95	61.9
6
Initial	92	3.90	94.8	−0.48	3.22	89.3	−0.89	83	3.80	91.8	−0.37	100.7
FU		5.01	121.0	1.90	4.01	110.5	0.89	80	3.92	91.0	−0.26	N/A
7
Initial	78	4.32	114.8	1.34	3.25	98.6	−0.12	75	2.59	67.9	−1.55	64.2
FU		5.71	150.5	4.56	3.97	119.3	1.61	70	2.72	70.7	−1.40	87.3
8
Initial	48	3.29	81.3	−1.55	2.97	83.2	−1.43	90	3.43	82.7	−0.83	54.1
FU		3.80	93.7	−0.51	3.20	89.5	−0.89	84	3.17	76.4	−1.15	64.8

		FVC			FEV1			Mean FEV1/FVC (%)	FEF 25–75
		Mean (L)	Mean (%)	Mean (z)	Mean (L)	Mean (%)	Mean (z)		Mean (L)	Mean (%)	Mean (z)
Initial		3.46	80.20	−1.72	2.89	76.39	−1.97	83.75	3.22	73.79	−1.29
FU		4.70	108.26	0.85	3.82	102.48	0.21	82.38	3.90	90.30	−0.50
P		0.0004	0.0001	0.0002	0.0022	0.0015	0.0014	0.6836	0.1317	0.1224	0.1473

Each individual flow-volume loop can be found in the Supplementary Appendix Figure S1.

DLCO, diffusing capacity of lung for carbon monoxide; FEF, forced expiratory flow; FEV1, forced expiratory volume in one second; FU, follow-up; FVC, forced vital capacity.