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. 2021 Apr 15;8:647720. doi: 10.3389/fcvm.2021.647720

Table 3.

Five-Year cumulative incidence of adverse events according to CRSS.

CRSS, 0 (a) CRSS > 0–6 (b) CRSS > 6–12 (c) CRSS > 12 (d) P-Value
Trend a vs. b* a vs. c* a vs. d* b vs. c* b vs. d* c vs. d*
All-cause death 5.6% (33) 2.4% (16) 7.6% (42) 8.9% (58) 0.001 0.195 0.235 0.01 0.015 <0.001 0.168
Cardiac death 3.3% (20) 1.6% (10) 3.2% (18) 6.5% (43) <0.001 0.282 0.929 0.006 0.259 <0.001 0.01
Myocardial infarction 3.0% (18) 3.9% (26) 4.2% (23) 10.6% (70) <0.001 0.058 0.049 <0.001 0.899 0.017 0.036
Unplanned revascularization 6.5% (39) 11.9% (79) 12.5% (69) 16.8 (110) <0.001 0.005 0.001 <0.001 0.448 0.007 0.081
Stroke 6.6% (39) 4.8% (32) 7.2% (40) 12.1% (80) <0.001 0.647 0.301 <0.001 0.139 <0.001 0.01
MACCE 17.6% (105) 17.9% (119) 25.1% (138) 33.6% (220) <0.001 0.216 <0.001 <0.001 0.019 <0.001 0.002

Event rates are Kaplan-Meier estimates, % (n).

*

Adjusted significance level is 0.008. CRSS, clinical residual SYNTAX score, MACCE, major adverse cardiovascular and cerebrovascular events.