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. 2021 Apr 15;12:657575. doi: 10.3389/fimmu.2021.657575

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Copyright © 2021 Zhang, Luan, Song, Cong, Ji, Zhou, Xia and Song

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Clinical outcomes in elderly and young patients receiving ICB treatment. The squares and vertical lines represent trial-specific HRs and 95% CIs. Red squares and orange background color indicate OS advantage in elderly patients and blue squares and green background color in young patients. The diamonds show the pooled estimate from fixed-effect meta-analysis. NSCLC, non-small cell lung cancer; RCC, renal cell carcinoma; GEJC, gastric or gastroesophageal junction carcinoma; SCLC, small cell lung cancer; HNC, head and neck cancer; TNBC, triple-negative breast cancer; MESO, mesothelioma.