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. 2021 Apr 15;12:660342. doi: 10.3389/fimmu.2021.660342

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Copyright © 2021 Halder and Lal

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Structure of human α3β4-nAChR complexes with nicotine. The human nAChR complex with α3β4 nicotine acetylcholine receptor (Protein data bank Id: 6PV7) is displayed using the online iCn3D software. The structure is composed of two α3 chains and three β4 chains. The Fab fragments of the antibody used for stabilization of the sample are shown at the top. Nicotine is shown in balls and sticks. Red and blue discs represent the plasma membrane. The thick arrow depicts the regulation of the movement of ions by the central pore.