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PCA of human colonic mucosa dataset with PAGA graph
(A) Top and bottom 15 gene loadings for the first three PCs.
(B) Proportion of total explained variance for each of the top 30 PCs.
(C) First two PCs plotted with Leiden cluster overlay.
(D) PAGA graph constructed from k-nearest neighbors (kNN) in 50-component PCA space (k = 46), describing relationships between Leiden clusters.
