TABLE 1.
Demographics and clinical variables by gender.
Variables | Males (n = 152) | Females (n = 76) | P-values |
Age, years | 75.3 ± 7.03 | 74.3 ± 7.04 | 0.33 |
Education, years | 15.8 ± 2.92 | 15.7 ± 2.86 | 0.81 |
APOE4 carriers, n (%) | 75 (49.3) | 35 (46.1) | 0.64 |
MMSE | 27.3 ± 1.7 | 27.4 ± 1.81 | 0.62 |
FDG SUVRs | 1.21 ± 0.13 | 1.21 ± 0.14 | 0.79 |
Plasma total testosteroneb (log10-transformed), ng/ml | 0.43 ± 0.19 | −0.36 ± 0.37 | <0.001 |
The number of subjects at each visit pointa | |||
Baseline | 152 | 76 | |
0.5 | 142 | 70 | |
1 | 128 | 68 | |
1.5 | 101 | 51 | |
2 | 106 | 58 | |
3 | 89 | 43 | |
4 | 47 | 32 | |
5 | 36 | 15 | |
6 | 27 | 20 | |
7 | 21 | 11 | |
8 | 2 | 4 | |
10 | 2 | 4 | |
11 | 3 | 5 | |
12 | 1 | 1 |
MMSE, Mini-Mental State Examination; FDG SUVRs, fluorodeoxyglucose standardized uptake value ratios. aParticipants who had FDG-PET measured were included. bThe non-transformed mean values for males and females were 2.94 ± 1 (mean ± SD) ng/ml and 0.57 ± 0.36 ng/ml, respectively.