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Different splicing sites and compositions form different circRNAs. (A) The splicing sites of pre-mRNA during the formation of intron circRNA (ciRNA) by intron circularization. (B) The splicing sites of pre-mRNA during exon and intron cyclization to form exon-intro circRNA (EIciRNA). (C-F) The splicing sites of pre-mRNA in the process exon cyclization to form exonic circRNA (ecircRNA).
