TABLE 1.
Demographic and baseline characteristics of the pediatric patients included in the population PK analysis (n = 108).
| Variables | Mean ± SD | Median (range) |
|---|---|---|
| Age (years) | 1.47 ± 2.63 | 0.456 (0.0164–13.0) |
| Body weight (kg) | 8.47 ± 9.22 | 5.40 (0.900–55.0) |
| Height (m) | 0.688 ± 0.278 | 0.600 (0.300–1.70) |
| BMI (kg/m2) | 14.1 ± 4.66 | 14.7 (3.60–34.3) |
| BSA (kgm2) | 0.388 ± 0.287 | 0.289 (0.132–1.65) |
| SCR(umol/L) | 25.6 ± 14.3 | 20.0 (9.00–83.0) |
| TBIL (umol/L) | 29.8 ± 43.4 | 9.05 (2.00–218) |
| ALT (U/L) | 21.9 ± 23.9 | 13.0 (1.00–129) |
| AST (U/L) | 34.1 ± 43.3 | 24.0 (7.00–418) |
| ALB (g/L) | 35.1 ± 6.19 | 36.0 (2.90–47.0) |
| WBC (e9/L) | 6.56 ± 2.93 | 6.00 (2.41–11.4) |
| ENC (%) | 47.8 ± 14.3 | 48.3 (1.20–93.3) |
BMI: body mass index; BSA: body surface area; SCR: serum creatinine; TBIL: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALB: albumin; WBC: white blood cell; ENC: eosinophils cell.