Skip to main content
. 2021 Apr 15;12:638993. doi: 10.3389/fphar.2021.638993

TABLE 1.

K a and P app values of some anthraquinone compounds absorbed in different intestines and colons of rats.

Duodenum Jejunum Ileum Colons References
K am (×10−4/s) P app (×10−5 cm/s) K a (×10−4/s) P app (×10−5 cm/s) K a (×10−4/s) P app (×10−5 cm/s) K a (×10−4/s) P app (×10−5 cm/s)
AE 5.43–16.07 7.65–10.68 4.88–13.03 6.29–9.83 2.23–8.63 3.45–5.90 3.88–12.17 5.12–7.9 (Wang et al., 2011a; Wang et al., 2011b; Qiu et al., 2011)
CH 19.02 13.77 15.15 12.88 10.80 10.27 18.17 15.22
EM 15.55 10.18 11.45 7.98 8.38 5.65 12.45 8.05
PH 10.08 5.53 6.38 3.83 6.22 4.00 16.12 12.42
RH 6.96–10.68 6.15–8.91 5.70–11.13 7.95–8.22 4.79–6.27 4.17–6.59 5.18–6.55 3.85–8.92

K a: absorption rate constant; P app: apparent absorption coefficient; AE: aloe-emodin; CH: chrysophanol; EM: emodin; PH: physcion; RH: rhein. The number of male and female rats in the studies was equal.