Comparison of radiologist performance to that of an artificial intelligence (AI) system. A, B, Jitter plots for the accuracy of the AI system for including, A, the correct top three differential diagnoses (T3DDx) and, B, correct top diagnosis (TDx) relative to the different groups of radiologists (radiology residents, general radiologists [General Rad], neuroradiology fellows [Neurorad fellows], and academic neuroradiologists [Academic Neurorads]). C, Nonparametric receiver operating characteristic (ROC) curves for the AI system (blue) compared with groups of radiologists based on their TDx, top two differential diagnoses, and T3DDx for each patient. D, E, Jitter plots for the accuracy of the AI system and radiologists for the, D, T3DDx and, E, exact correct TDx as a function of disease prevalence: common (black circle), moderately rare (gray square) and rare (white triangle). Solid lines denote the mean, and error bars represent standard error of measurement.