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. 2021 Apr 15;12:573909. doi: 10.3389/fphar.2021.573909

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Copyright © 2021 Hao, Sun, Zhu, Xie, Wang, Jiang, Fu and Sang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution and expression of HPV18 E6, E7, P53, and Rb1 in cancer tissues. IHC staining of HPV18 E6, E7, P53, and Rb1 protein in tumor samples monoclonal antibody. Tumor sections immunostained with E6 (A), E7 (B), P53 (C), and Rb1 (D) antibodies in mice treated with RES or RHSD (scale bar = 20 μm). The histogram on the right is the quantitative analysis of the results. The data were presented as the mean ± S.D. for three different experiments performed in triplicate. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.