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. 2021 Apr 15;12:573909. doi: 10.3389/fphar.2021.573909

TABLE 1.

Variation of the 1H NMR chemical shifts (ppm) of Res and HP-β-CD protons in free and complex states determined in DMSO-d6.

Substance Proton Free (δ) Complex (δ) ∆δ
Res H-2,6 6.338 6.333 −0.005
H-4 6.069 6.065 −0.004
α 6.785 6.784 −0.001
β 6.898 6.897 −0.001
H-2′, 6′ 7.358 7.358 0
H-3′, 5′ 6.716 6.715 +0.001
HP-β-CD H-1 4.791 4.791 0
H-2 3.396 3.396 0
H-3 3.705 3.702 −0.003
H-4 3.259 3.259 0
H-5 3.517 3.515 −0.002
H-6 3.570 3.570 0