FIGURE 1.

Epithelial barrier function and macromolecule flux after Campylobacter jejuni infection in epithelial cell monolayers and after treatment with resveratrol. Human intestinal epithelial HT-29/B6 cells were treated with 100 µM of resveratrol from apical and infected apically with C. jejuni (multiplicity of infection; MOI 100). Transepithelial electrical resistance (TER) was measured with chopstick electrodes 48 h after the infection (A) Resveratrol inhibits the C. jejuni-induced decrease in TER in vitro. Control values after 48 h were set at 100% (n = 9–10, **p < 0.01, one-way ANOVA with Bonferroni correction). (B) Resveratrol prevents C. jejuni-induced increase in permeability to fluorescein (332 Da) in vitro (n = 10, *p < 0.05, **p < 0.01, one-way ANOVA with Bonferroni correction).