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. 2021 Apr 15;12:640572. doi: 10.3389/fphar.2021.640572

FIGURE 6.

FIGURE 6

In vitro stimulation model with cytokines and resveratrol. Cytokine-induced barrier dysfunction from the subepithelial compartment of HT-29/B6-GR/MR cell monolayers. Resveratrol treatment was performed from the apical side 2 h before cytokine addition. Fluorescein permeability displays barrier-breaking effects for (A) 50 ng/ml IFN-γ and (B) high-dose cytokine cocktail containing 100 U/mL TNF-α, and 100 ng/ml IL-1β, 50 ng/ml IFN-γ (n = 3–8, *p < 0.05, ***p < 0.001, one-way ANOVA with Bonferroni correction).