Table 3. Recommended vancomycin as per ARC stratification.

Mahmoud SH, Shen C: Augmented Renal Clearance in Critical Illness: An Important Consideration in Drug Dosing. Pharmaceutics. 2017, 9:10.3390/pharmaceutics9030036 [7]

ARC: augmented renal clearance; eGFR: estimated glomerular filtration rate

ARC stratification CrCl(mL/min/1.73m2)	Recommended interval dosing of vancomycin
Mild 130–150	15-20 mg/kg q8-12 hr (up-to 4 gm/day)
Moderate 150–200	3–4 g/day
High ARC 200–250	4–4.5 g/day
Very high ARC 250–300	4.5–5.5 g/day
extreme ARC >300	6.0 g/day