Table 1.

Metal homeostasis within immune cells

	Iron	Zinc	Copper
Macrophages	DMT1 [42] Transferrin Receptor 1 (TFR1) [45] Slc39a14 (ZIP14) [77] Lactoferrin receptor (LfR) [43] CD163 [45] CD64 [220] Ferroportin (FPN) [50] Lipocalin-2 (LCN-2) [63] Nramp-1 [45] Hepcidin [53]	SLC39A (ZIP) Slc39a2 [77] Slc39a4 [77] Slc39a14 [77] SLC30A (ZnTs) Slc30a1 [77] Slc30a3 [77] Slc30a5 [77]	CTR1 [84] ATP7A [84]
Neutrophils	Nramp-1 [63] Lipocalin-2 [63] Myeloperoxidase [113] Ceruloplasmin [119] Lactoferrin [110]	Calprotectin (S100A8/S100A9 heterodimer) [13] Calgranulin C (S100A12) [124]	Calgranulin C (S100A12) [124] ATP7A [118] ATP7B [118] Ceruloplasmin [119]
NK cells	TfR1 (CD71) [183] Lactoferrin receptor (LfR) [185]	KIR receptor [188] Surface receptors with tyrosine phosphorylation sites [190]	Unknown
Dendritic cells	Unknown	ZIPs and ZNTs [102]	Unknown
Basophils	Unknown	Methallothioneins (MTs) [158]	Unknown
Eosinophils	Eosinophil peroxidase (EPX) [152]	Unknown	Unknown
Mast cells	Unknown	Unknown	Ctr2 [161]
ɣδ T cells	Lactoferrin receptor (LfR) [195] Hereditary hemochromatosis susceptibility gene (HFE) [197, 198] Β2-microglobulin (βm-2) [198]	Unknown	Unknown
iNKT cells	Ferroportin (FPN) [201] Hepcidin [201]	Unknown	Unknown
MAIT cells	Unknown	Unknown	Unknown
T cells	TfR1 (CD71) [209] Lactoferrin receptor (LFR) [195]	Unknown	Unknown
B cells	TfR1 (CD71) [209]	Unknown	Unknown