Fig. 4.

Optical coherence tomography scan of the macula (Optovue Avanti; image dimensions, 3 × 3mm). A B-scan through the fovea (A) and en face image (B) of the 3 μm thick projection extracted from the depth indicated by the red line in the B-scan (A). The red line in the en face projection (B) indicates the vertical location of the displayed B-scan from (A). In (B), a dark void surrounds the centrally spared foveal cones, thought to correspond with an area of reduced cone outer segment size. Peripheral to this area, there are patches of darkened reflectivity, likely representing variable cone integrity and a reduction in outer segment size. Scale bars are all 300 μm. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)