TABLE 3.
Stratified Analyses for Mortality in USA300 Methicillin-Resistant Staphylococcus aureus Invasive Infections
Stratification (n = no. of studies) | OR (95% CI) | Heterogeneity | ||
---|---|---|---|---|
Fixed-effects model | Random-effects model | Q | P | |
Main analysis (n = 8) | 0.65 (0.53–0.81) | 0.63 (0.49–0.81) | 8.54 | .29 |
Stratified analyses | ||||
Study location | ||||
Multicentera (n = 6) | 0.67 (0.54–0.83) | 0.67 (0.53–0.84) | 5.27 | .38 |
Study design | ||||
Prospective (n = 4) | 0.69 (0.52–0.90) | 0.60 (0.37–0.97) | 5.15 | .16 |
Retrospective (n = 4) | 0.61 (0.43–0.85) | 0.61 (0.43–0.85) | 3.08 | .38 |
Overall quality of studies | ||||
High (8–9 points) (n = 4) | 0.66 (0.51–0.85) | 0.58 (0.39–0.87) | 5.50 | .14 |
Low (0–7 points) (n = 4) | 0.64 (0.44–0.95) | 0.65 (0.44–0.95) | 3.04 | .39 |
Definition of mortality | ||||
Non-infection-related mortalityb (n = 6) | 0.65 (0.51–0.84) | 0.60 (0.42–0.86) | 7.39 | .19 |
NOTE. CI, confidence interval; OR, odds ratio.
There were not enough single-center studies to pool the results.
There were not enough studies assessing attributable mortality to pool the results.