Table III.
Statistical comparison of environmental and clinical factors for genetic and non-genetic SNHL.
| Cohort | |||
|---|---|---|---|
| Risk factors | Screening (N=854) | Genetic (N=34) | P-value (test) |
| Gender=Female | 432/854 (50.6%) | 20/34 (58.8%) | 0.384943 (Fisher exact) |
| Environment=Urban | 563/852 (66.1%) | 16/34 (47.1%) | 0.027233 (Fisher exact) |
| Prematurity=Yes | 115/854 (13.5%) | 9/34 (26.5%) | 0.042056 (Fisher exact) |
| Gestational age | 39 [38.00, 39.00] | 38 [36.00, 40.00] | 0.138 (Mann-Whitney) |
| Apgar score | 8.38±0.8694 | 8.41±0.9883 | 0.826370 (Student T) |
| Mother's age | 28.84±5.951 | 26.79±4.841 | 0.048529 (Student T) |
| Maternal pathologies=Yes | 164/854 (19.2%) | 9/34 (26.5%) | 0.275933 (Fisher exact) |
| Chemicals, Radiation=Yes | 1/854 (0.1%) | 0/34 (0.0%) | 1.000000 (Fisher exact) |
| Ototoxic medication for mother=Yes | 88/854 (10.3%) | 8/34 (23.5%) | 0.023347 (Fisher exact) |
| Birth complications=Yes | 50/854 (5.9%) | 3/34 (8.8%) | 0.449632 (Fisher exact) |
| Congenital infections=Yes | 110/854 (12.9%) | 3/34 (8.8%) | 0.608554 (Fisher exact) |
| Periintraventricular hemorrhage=Yes | 22/854 (2.6%) | 1/34 (2.9%) | 0.597264 (Fisher exact) |
| Respiratory distress=Yes | 46/854 (5.4%) | 3/34 (8.8%) | 0.427561 (Fisher exact) |
| Perinatal hypoxia=Yes | 98/854 (11.5%) | 4/34 (11.8%) | 1.000000 (Fisher exact) |
| Mechanical ventilation=Yes | 81/854 (9.5%) | 4/34 (11.8%) | 0.558063 (Fisher exact) |
| Neonatal Intensive Care (NICU)=Yes | 78/854 (9.1%) | 4/34 (11.8%) | 0.545578 (Fisher exact) |
| Neonatal hypotension=Yes | 37/854 (4.3%) | 0/34 (0.0%) | 0.393117 (Fisher exact) |
| Hypoxic ischemic encephalopathy (HIEP),=Yes | 3/853 (0.4%) | 0/34 (0.0%) | 1.000000 (Fisher exact) |
| Hyperbilirubinemia=Yes | 135/854 (15.8%) | 3/34 (0.0%) | 0.341235 (Fisher exact) |
| Cranial trauma=Yes | 56/854 (6.6%) | 0/34 (0.0%) | 0.265235 (Fisher exact) |
| Ototoxic medication for NB=Yes | 64/854 (7.5%) | 5/34 (14.7%) | 0.176912 (Fisher exact) |
| Craniofacial abnormalities=Yes | 1/854 (0.1%) | 0/34 (0.0%) | 1.000000 (Fisher exact) |
| Other abnormalities=Yes | 91/853 (10.7%) | 4/34 (11.8%) | 0.777523 (Fisher exact) |
| Very Low Birth Weight (VLBW) | 18/854 (2.1%) | 0/34 (0.0%) | 1.000000 (Fisher exact) |
| Extremely Low Birth Weight (ELBW) | 8/854 (0.9%) | 0/34 (0.0%) | 1.000000 (Fisher exact) |