Table 6.
Grouping/species | SGM other than MAC and M. kansasii (n = 50) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Antimicrobial agent | Broth dilution ranges (μg/ml) | MIC50 | MIC90 | Susceptible | Intermediate | Resistant | S (%) | I (%) | R (%) |
Antimicrobial agents and susceptibility breakpoints (MICs) for testing SGM other than MAC and M. kansasiia | |||||||||
Amikacin | 1‒64 | 4 | 32 | ≤ 16 | 32 | ≥ 64 | 86 | 6 | 8 |
Ciprofloxacin | 0.12‒16 | 4 | > 16 | ≤ 1 | 2 | ≥ 4 | 12 | 24 | 64 |
Clarithromycin | 0.06‒64 | 0.5 | 4 | ≤ 8 | 16 | ≥ 32 | 94 | 0 | 6 |
Doxycycline | 0.12‒16 | > 16 | > 16 | ≤ 1 | 2‒4 | ≥ 8 | 8 | 10 | 82 |
Linezolid | 1‒64 | 8 | 64 | ≤ 8 | 16 | ≥ 32 | 58 | 4 | 38 |
Moxifloxacin | 0.12‒8 | 2 | > 8 | ≤ 1 | 2 | ≥ 4 | 50 | 24 | 26 |
Rifampicin | 0.12‒8 | 2 | > 8 | ≤ 2 | - | ≥ 4 | 56 | - | 44 |
Rifabutin | 0.25‒8 | 0.5 | 1 | ≤ 1 | - | ≥ 2 | 96 | - | 4 |
TMP‒SMX | 0.12/2.38‒8/152 | 2 | > 8 | ≤ 2/38 | - | ≥ 4/76 | 46 | - | 54 |
SGM slow growing mycobacteria, MAC Mycobacterium avium‒intracellulare complex, CLSI Clinical and Laboratory Standards Institute, TMP‒SMX trimethoprim-sulfamethoxazole
aCLSI M24, 3rd ed., 2018 (2)