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. 2021 Apr 15;12:626972. doi: 10.3389/fphar.2021.626972

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Copyright © 2021 Wang, Yu, Luo, Sun, Yu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Screening the differential expression genes (DEGs) in ESCC-nCRT responder and non-responder samples. (A) Volcano plot visualized the distribution of DEGs. Red dots represented up-regulated genes and blue dots were down-regulated genes. The overlapped genes were named in figures represented the up-regulated or down-regulated genes in both datasets. (B) Bidirectional clustering analysis of DEG in nCRT responder and non-responder samples. These genes are overlapped genes dysregulated in both datasets. The color changed from blue to red represented the expression level from low to high.