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. Author manuscript; available in PMC: 2021 Jul 17.
Published in final edited form as: ACS Chem Biol. 2020 Jul 2;15(7):1996–2004. doi: 10.1021/acschembio.0c00390

Figure 4.

Figure 4.

A) Copper and zinc homeostasis gene expression. Growth of WT and Δrna strains in the presence of various concentrations of CuSO4 under aerobic (B) and anaerobic (C) conditions. Differences between WT and Δrna at each concentration under aerobic conditions are not significant. Anaerobic data significance calculated by ANOVA for WT vs. Δrna strains; 0 μM and 0.7 μM, P < 0.0004; 3.125 μM, P < 0.017. D) Differential expression of genes related to metabolism. E) Levels of intracellular metals in WT and Δrna cells grown +/- O2.