Table 3.
Differentially expressed genes in enriched pathways associated with vascular change during pregnancy
| Genes | logFC | Adjusted P Value |
|---|---|---|
| Endocytosis (rno04144) | ||
| RT1-T24-1 | −1.8954104 | 0.00016123 |
| RT1-CE5 | −0.9521472 | 0.00065068 |
| RT1-T24-3 | −1.5051583 | 0.00069523 |
| Washc5 | 0.41562476 | 0.00124156 |
| Igf2r | 0.73143706 | 0.00807887 |
| Ap2s1 | −0.4407505 | 0.01069065 |
| Gbf1 | 0.36912001 | 0.01732892 |
| Egfr* | 0.52666122 | 0.01836792 |
| Ap2b1 | 0.55158071 | 0.02562886 |
| Tfrc* | 0.41008398 | 0.02729657 |
| Vps35* | 0.24749648 | 0.03275091 |
| Vps28* | −0.2918485 | 0.03732335 |
| Rab31 | 0.2307909 | 0.04102501 |
| Stam2 | 0.60099759 | 0.04125232 |
| Ubb* | −0.4214775 | 0.04191601 |
| Arrb1* | 0.2979953 | 0.04304641 |
| Vps26b* | 0.20272241 | 0.04646427 |
| Cell adhesion molecule (rno04514) | ||
| RT1-T24-1* | −1.8954104 | 0.00016123 |
| RT1-CE5* | −0.9521472 | 0.00065068 |
| RT1-T24-3* | −1.5051583 | 0.00069523 |
| RT1-Bb* | 1.34228528 | 0.00260124 |
| Cldn5* | −0.7695119 | 0.00636124 |
| Glg1* | 0.8652644 | 0.0084503 |
| Itga8* | 0.93041203 | 0.02562886 |
| RT1-Ba* | 0.83828736 | 0.02636128 |
| Itga9* | 0.88436668 | 0.02651378 |
| F11r* | −0.4457938 | 0.03561501 |
| Itgam* | 0.53418603 | 0.04984969 |
| Vascular smooth muscle contraction (rno04270) | ||
| Pla2g12a | −0.5066628 | 0.00528555 |
| Gna11 | 0.47734613 | 0.00911017 |
| Ramp2 | −0.4783029 | 0.01543466 |
| Edn1* | −1.0713506 | 0.01925476 |
| Pla2g2d | 1.7306706 | 0.02330807 |
| Arhgef1* | −0.3051994 | 0.02332887 |
| Adora2b | −0.6417687 | 0.02562886 |
| Rock1 | 0.5090851 | 0.03524969 |
| Scart1 | −2.4974685 | 0.03916115 |
| Pla2g4b* | −0.4119394 | 0.03942963 |
| Avpr1a | 0.88118128 | 0.04108323 |
| Itpr1 | 0.6847391 | 0.04908477 |
FC, fold change. *Unique to pregnancy.