Figure 7.

Spiral wave dynamics in two-dimensional (2-D) tissue with the 1991 Luo and Rudy (LR1) model. A: spiral wave behaviors vs. G_si and G_to with the original I_si kinetic. The magenta circle and arrow mark the parameter set of the original LR1 model (control). B: spiral wave behaviors vs. G_si and G_to for a speedup I_si kinetics. To speed up the kinetics of I_si, the time constants of the activation and inactivation gates were reduced by multiplying a factor 0.3, i.e., ${\tau }_d\to 0.3{\tau }_d$ and ${\tau }_f\to 0.3{\tau }_f$. C: voltage snapshots showing spiral waves for the speedup I_si kinetics for G_si = 0.09 mS/µF and different G_to as indicated on each panel.