Table 2.
Summary of the clinical MRI and SWE parameters for the 62 patients
| Parameters | Responder (n = 34) | Non-responder (n = 28) | p value |
|---|---|---|---|
| MRI volume (mm3) | |||
| VMRI1 | 104,589.2 ± 254,548.7 (24) | 117,407.7 ± 164,022.0 (25) | 0.17 |
| VMRI2 | 24,458.6 ± 65,700.82 (16) | 115,921.4 ± 131,323.6 (7) | 0.09 |
| VMRI3 | 16,939 ± 52,964.8 (14) | 72,912.7 ± 123,127.2 (14) | 0.04* |
| Mass size (mm) | |||
| s1 | 27.1 ± 13.7 (28) | 34 ± 20.5 (28) | 0.27 |
| s2 | 16.5 ± 8.5 (32) | 29.0 ± 16.5 (26) | < 0.001* |
| s3 | 10.6 ± 6.6 (25) | 24.3 ± 15.4 (24) | < 0.001* |
| Mean elasticity (kPa) | |||
| Emean1 | 82.2 ± 38.0 (28) | 92.1 ± 32.9 (28) | 0.76 |
| Emean2 | 38.5 ± 22.7 (32) | 60.0 ± 30.3 (26) | 0.01* |
| Emean3 | 29.5 ± 25.4 (25) | 47.6 ± 33.3 (24) | 0.03* |
| Maximum elasticity (kPa) | |||
| Emax1 | 163.1 ± 55.7 (28) | 179.6 ± 38.6 (28) | 0.50 |
| Emax2 | 95.7 ± 51.1 (32) | 134.9 ± 59.0 (26) | 0.01* |
| Emax3 | 63.4 ± 49.8 (25) | 114.3 ± 72.9 (24) | 0.02* |
| Ratio of mean elasticity | |||
| Emean-ratio1 | 16.2 ± 14.8 (28) | 26.0 ± 21.2 (28) | 0.02* |
| Emean-ratio2 | 10.9 ± 10.2 (32) | 16.8 ± 14.9 (26) | 0.07 |
| Emean-ratio3 | 5.3 ± 6.1 (25) | 10.8 ± 9.8 (24) | 0.02* |
| Ratio of maximum elasticity | |||
| Emax-ratio1 | 16.6 ± 14.0 (28) | 22.2 ± 14.0 (28) | 0.08 |
| Emax-ratio2 | 14.3 ± 15.1 (32) | 23.0 ± 31.8 (26) | 0.22 |
| Emax-ratio3 | 6.1 ± 5.5 (25) | 15.6 ± 16.2 (24) | 0.02* |
| Mass characteristic frequency (Hz) | |||
| fmass1 | 125.7 ± 71.2 (28) | 119.1 ± 74.8 (28) | 0.82 |
| fmass2 | 135.3 ± 72.2 (32) | 105.0 ± 79.2 (26) | 0.05 |
| fmass3 | 243.9 ± 156.3 (25) | 102.2 ± 61.2 (24) | < 0.001* |
| Change of elasticity (kPa) | |||
| Emean1–2 | 39.8 ± 35.9 (26) | 31.3 ± 42.4 (26) | 0.42 |
| Emean1–3 | 50.9 ± 41.4 (19) | 45.6 ± 43.1 (24) | 0.46 |
| Emax1–2 | 57.2 ± 60.8 (26) | 48.5 ± 69.7 (26) | 0.50 |
| Emax1–3 | 102.7 ± 56.0 (19) | 65.8 ± 77.3 (24) | 0.09 |
| Change of mass characteristic frequency (Hz) | |||
| fmass1–2 | −8.9 ± 97.6 (26) | 16.1 ± 86.3 (26) | 0.90 |
| fmass1–3 | −88.4 ± 98.4 (19) | 16.1 ± 55.4 (24) | < 0.001* |
Data are mean ± standard deviation; data in parentheses are mass numbers
Emean mean elasticity, Emax maximum elasticity, Emean_ratio ratio of the mean elasticity between the mass and the surrounding normal tissue, Emax_ratio ratio of the maximum elasticity between the mass and the surrounding normal tissue, fmass mass characteristic frequency
The subscripts 1, 2, and 3 indicate the corresponding parameters measured at the first, the second, and the third visit, respectively
*p < 0.05; the difference is statistically significant