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. Author manuscript; available in PMC: 2021 Apr 29.
Published in final edited form as: Environ Int. 2020 Mar 20;138:105623. doi: 10.1016/j.envint.2020.105623

Table A2.

Results of simulated screening experiments on 26 datasets using active learning and recall estimation with δ = 2. Mean and standard deviation over 30 trials with initially randomized order.

Records from Search % Screened Cost Theoretical WSS@95 Obtained WSS@95 Estimated Recall Obtained True Recall
Transgenerational inheritance of health effects 48,638 0.371 0.128 0.742 (0.003) 0.613 (0.001) 0.950 0.986 (0.001)
Neuropathic pain 29,207 0.402 0.040 0.613 (0.001) 0.573 (0.022) 0.950 0.976 (0.014)
USDA 2 9,103 0.332 0.099 0.755 (0.004) 0.655 (0.010) 0.950 0.987 (0.001)
Bisphenol A (BPA) and obesity 7,700 0.354 0.161 0.807 (0.010) 0.646 (0.013) 0.950 1.000 (0.000)
PFOA/PFOS and immunotoxicity 6,331 0.448 0.280 0.833 (0.009) 0.552 (0.010) 0.950 1.000 (0.000)
Fluoride and neurotoxicity in animal models 4,479 0.443 0.324 0.862 (0.018) 0.538 (0.009) 0.950 0.981 (0.004)
Statins 3,465 0.576 0.024 0.399 (0.035) 0.375 (0.015) 0.950 0.951 (0.002)
Ace inhibitors 2,544 0.550 0.333 0.758 (0.023) 0.425 (0.013) 0.950 0.976 (0.000)
Beta blockers 2,072 0.629 0.262 0.586 (0.016) 0.324 (0.014) 0.950 0.953 (0.004)
Opioids 1,915 0.856 0.114 0.257 (0.028) 0.144 (0.038) 0.950 1.000 (0.000)
USDA 1 1,776 0.445 0.116 0.659 (0.007) 0.543 (0.009) 0.950 0.988 (0.004)
Skeletal muscle relaxants 1,643 0.902 0.191 0.289 (0.065) 0.098 (0.013) 0.950 1.000 (0.000)
USDA 5 1,570 0.704 0.328 0.624 (0.040) 0.296 (0.018) 0.950 1.000 (0.000)
Mammalian 1,442 0.580 0.121 0.529 (0.015) 0.408 (0.014) 0.950 0.988 (0.004)
Proton pump inhibitors 1,333 0.743 0.139 0.397 (0.018) 0.257 (0.009) 0.950 1.000 (0.000)
Calcium Channel Blockers 1,218 0.620 0.194 0.563 (0.021) 0.369 (0.024) 0.950 0.989 (0.005)
Atypical Antipsychotics 1,120 0.680 −0.070 0.165 (0.020) 0.235 (0.014) 0.950 0.915 (0.016)
ADHD 851 0.694 0.474 0.734 (0.046) 0.259 (0.017) 0.950 0.953 (0.013)
Triptans 671 0.782 0.240 0.458 (0.030) 0.218 (0.012) 0.950 1.000 (0.000)
USDA 3 608 0.863 0.094 0.231 (0.068) 0.137 (0.018) 0.950 1.000 (0.000)
Oral Hypoglycemics 503 0.835 −0.009 0.092 (0.018) 0.101 (0.019) 0.951 0.936 (0.039)
Nonsteroidal anti-inflammatory 393 0.632 0.254 0.621 (0.019) 0.368 (0.013) 0.950 1.000 (0.000)
Estrogens 368 0.664 0.129 0.454 (0.021) 0.325 (0.013) 0.951 0.989 (0.006)
Urinary Incontinence 327 0.798 0.199 0.401 (0.018) 0.202 (0.020) 0.951 1.000 (0.000)
Antihistamines 310 0.829 −0.042 0.072 (0.034) 0.115 (0.025) 0.951 0.944 (0.019)
USDA 4 104 0.846 0.325 0.479 (0.070) 0.154 (0.019) 0.952 1.000 (0.000)