Table 3.

Multivariate and univariate Cox regression analysis on mortality at 30-day models

	Univariate analysis hazard ratio (95% CI)	p value	Multivariate analysis hazard ratio (95% CI)	p value
Age, y	1.06 (1.02–1.07)	< 0.001	1.05 (1.02–1.08)	< 0.001
Cancer	3.13 (1.75–5.63)	< 0.001	1.88 (0.96–3.70)	0.067
Respiratory rate	1.06 (1.03–1.10)	0.001	1.06 (1.01–1.11)	0.020
Oxygen saturation	0.96 (0.94–0.97)	< 0.001	0.98 (0.96–1.01)	0.280
Creatinine	1.00 (1.00–1.01)	0.007	1.00 (1.00—1.01)	0.226
C-reactive protein	1.00 (1.00–1.01)	0.007	1.00 (1.00–1.01)	0.696
Brain natriuretic peptide	1.00(1.00–1.00)	< 0.001	1.00 (1.00–1.00)	0.049
Hemoglobin	0.74 (0.65–0.84)	< 0.001	0.80 (0.69–0.93)	0.004
CT severity score < 7/≥ 7 adding GGO and consolidation	4.33 (2.25–8.32)	< 0.001	3.16 (1.50–6.43)	0.001
COPD	2.41 (1.08–5.36)	0.032
DBP	0.98 (0.96–1.00)	0.015
High-sensitivity Troponin I	1.00 (1.00–1.00)	0.034
Lymphocytes	1.03 (1.01–1.04)	0.008
Heart rate, bpm	0.98 (0.97–1.00)	0.039
Oral anticoagulant	2.34 (1.17–4.70)	0.017
Coronary artery disease	1.92 (0.86–4.29)	0.110
History of heart failure	1.64 (0.40–6.78)	0.492
Hypercholesterolemia	0.93 (0.49–1.75)	0.811
History of smoking	0.77 (0.39–1.50)	0.437
Days from illness onset to CT	0.99 (0.89–1.05)	0.891
D-dimer, μg/mL	1.00 (1.00–1.00)	0.299
Male	0.84 (0.46–1.53)	0.570
BMI	1.00 (0.94–1.07)	0.953
Statins	0.70 (0.327–1.494)	0.356
Aspirin	0.97 (0.45–2.06)	0.926
Diabetes mellitus	0.85 (0.42–1.71)	0.652
Hypertension	1.49 (0.85–2.63)	0.167

Footnotes: Hazard ratio (HR) is calculated with each per unit-increase. Abbreviations: CI, confidence interval; COPD, chronic obstructive pulmonary disease; BMI, body mass index in kg/m²; DBP, diastolic blood pressure