Table 1.
Pupillary Light Reflex Responses and Peripapillary RNFL Thickness in Patients With MS and Healthy Control Subjects
| Healthy | Patients With | Cohen's d | ||
|---|---|---|---|---|
| Controls (n = 25) | MS (n = 25) | P Valuea | Effect Size | |
| Initial pupil diameter (mm) | 6.12 ± 0.69 | 5.39 ± 0.74 | 0.003 | 1.0243 |
| Contraction amplitude (mm) | 1.76 ± 0.23 | 1.55 ± 0.37 | 0.027 | 0.6884 |
| Percentage change in size (%) | 29.1 ± 4.5 | 28.8 ± 5.2 | 0.818 | 0.0641 |
| Contraction latency (ms) | 276.0 (249.5–289.0) | 287.0 (249.5–307.5) | 0.435 | −0.2199 |
| Contraction duration (ms) | 613.4 ± 77.5 | 577.2 ± 68.4 | 0.102 | 0.4963 |
| Contraction velocity (mm/s) | 5.42 (5.10–6.28) | 4.95 (4.63–5.80) | 0.185 | 0.3917 |
| Dilation latency (ms) | 869.0 (847.0–901.0) | 868.0 (815.5–898.5) | 0.148 | 0.4221 |
| Dilation duration (ms) | 1600.0 (1582.5–1633.0) | 1628.0 (1574.0–1649.5) | 0.119 | −0.4828 |
| Dilation velocity (mm/s) | 1.85 ± 0.40 | 1.89 ± 0.32 | 0.660 | −0.1224 |
| RNFL thickness (µm) | 101.3 ± 8.5 | 85.1 ± 13.5 | <0.001 | 1.4400 |
Data are expressed as mean ± SD for parametric variables and median (IQR) for nonparametric variables.
a
Binomial logistic regression analysis.