Table 2.
Cytotoxicity of VHL-based PROTACs in Pancreatic Cancer Cell Lines
 | |||||
|---|---|---|---|---|---|
| ID | Linker | MW | cLogP | IC50 (μM) | |
| MIA PaCa-2 | BxPC-3 | ||||
| 9–4a |  |
799.90 | 3.82 | 14.5 ± 7.1 | >30 |
| 9–4b |  |
755.84 | 3.99 | 15.8 ± 4.6 | >30 |
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