Table 4.

Upregulated Proteins Exclusive to XD2–149 Treatment in BxPC-3 Cells

No	Gene Symbol	Name	Log2FCa	p-valueb
1	JUN	Transcription factor AP-1	1.58	<0.001
2	ARX	Homeobox protein ARX	1.54	0.043
3	DNAJB9	DnaJ homolog subfamily B member 9	1.35	<0.001
4	IL1RL1	Interleukin-1 receptor-like 1	1.24	0.010
5	SYNC	Syncoilin	1.04	0.045
6	RND3	Rho-related GTP-binding protein RhoE	0.98	0.001
7	HMGCR	3-hydroxy-3-methylglutaryl-coenzyme A reductase	0.83	0.009
8	ZNF430	Zinc finger protein 430	0.77	0.039
9	ECM1	Extracellular matrix protein 1	0.76	0.026
10	RHOB	Rho-related GTP-binding protein RhoB	0.73	0.035
11	GDF15	Growth/differentiation factor 15	0.69	0.010
12	ABCB6	ATP-binding cassette sub-family B member 6, mitochondrial	0.68	0.025
13	AFF1	AF4/FMR2 family member 1	0.67	0.049
14	MPV17	Protein Mpv17	0.66	0.049
15	EPHB3	Ephrin type-B receptor 3	0.65	0.024
16	UGCG	Ceramide glucosyltransferase	0.62	0.032
17	AKR1C2	Aldo-keto reductase family 1 member C2	0.6	0.004
18	BACH1	Transcription regulator protein BACH1	0.6	0.004

^aFC > 1.5.

^bp-value ≤ 0.05.