Table 3.
Univariate analysis (Chi-squared test/T-student test). Variables associated with recurrence and tumor death
| Event | Feature | p | OR (95% CI) | |||
|---|---|---|---|---|---|---|
| Recurrence | Age [mean dif. (SD)] | 0.017 | 4.47 (1.86) | |||
| Laurén subtype | 0.017 | Intestinal | 1 | |||
| Diffuse | 2.32 (1.25-4.3) | |||||
| Mixed | 0.86 (0.3-2.48) | |||||
| Signet-ring cells | 0.056 | 1.69 (0.95-3.03) | ||||
| Perineural invasion | 0.035 | 1.98 (1.11-3.52) | ||||
| Intrat. IIa | 0.035 | None | 1 | |||
| Mild-mod | 0.09 (0.01-0.76) | |||||
| Severe | 0.08 (0.01-0.65) | |||||
| pT | 0.06 | T1 | 1 | |||
| T2 | 1.71 (0.32-9.29) | |||||
| T3 | 4 (0.82-19.62) | |||||
| T4 | 3.67 (0.64-21.15) | |||||
| pN | 0.038 | N0 | 1 | |||
| N1 | 1.75 (0.74.4,15) | |||||
| N2 | 1.95 (0.88-4.33) | |||||
| N3 | 3.37 (1.46-7.81) | |||||
| pTNM stage | 0.007 | I | 1 | |||
| II | 3.16 (1.07-9.35) | |||||
| III | 4.92 (1.71-14.16) | |||||
| LNR [mean dif. (SD)] | 0.006 | 0.11 (0.41) | ||||
| Adjuvant therapy | <0.001 | 4.52 (2-10.21) | ||||
| Tumor death | Age [mean dif. (SD)] | 0.027 | 4.92 (2.21) | |||
| Laurén subtype | 0.003 | Intestinal | 1 | |||
| Diffuse | 3.59 (1.7-7.58) | |||||
| Mixed | 1.66 (0.47-5.88) | |||||
| Signet-ring cells | 0.006 | 2.68 (1.32-5.43) | ||||
| High grade | 0.008 | 2.67 (1.28-5.58) | ||||
| LVb invasion | 0.059 | 1.94 (0.97-3.86) | ||||
| Infiltrative front | 0.069 | 2 (0.94-4.25) | ||||
| Desmoplasia | 0.035 | 0.48 (0.24-0.95) | ||||
| pN | 0.001 | N0 | 1 | |||
| N1 | 1.4 (0.5-3.94) | |||||
| N2 | 0.53 (0.18-1.59) | |||||
| N3 | 3.93 (1.5-10.28) | |||||
| pTNM | 0.072 | I | 1 | |||
| II | 4 (0.84-10.13) | |||||
| III | 5.21 (1.16-24.1) | |||||
| LNR [mean dif. (SD)] | 0.007 | 0.16 (0.048) | ||||
| Recurrence | <0.001 | 20.9 (7.64-57.13) | ||||
| Adjuvant therapy | 0.005 | 3.12 (1.38-7.07) | ||||
aIntrat. II: Intratumoral inflammatory infiltrate. bLV: Lymphovascular