Table 3.
MSA Log Likelihood N for SARS, MERS, and SARS-CoV-2
| Amino Acids | Nucleotides | |||
|---|---|---|---|---|
| Fraction Matching (0–1) | MSA Log Likelihood | Fraction Matching (0–1) | MSA Log Likelihood | |
| SARS N | 1 | 0 | 1 | 0 |
| MERS N | 0.448 | –3.079 | 0.510.448 | –2.651 |
| SARS-CoV-2 N | 0.891 | 0.530 | 0.8701 | 0.687 |
Multiple sequence alignment performed with the N for coronaviruses SARS, MERS, and SARS-2 indicates a high similarity between SARS-CoV and SARS-CoV-2 (89% matching residues). MERS, however, partially mirrors SARS-CoV-2 with only 44% aligning residues. Conservation results indicate the potential for a SARS homologue.
Abbreviations: MERS, Middle East respiratory syndrome; N, nucleocapsid; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.