Table 4.

Kappa statistics: Tumour budding-H and E and pancytokeratin (score)

Tumour Budding H&E (Score)	Counts and percentages (%) within BD score	Tumour budding pancytokeratin (score)			Total
		Score 0	Score 1	Score 2
Tumour budding H and E (score)
Score 0	Count	2	1	5	8
	Percentage within tumour budding pancytokeratin (score)	100.0	33.3	20.0	26.7
Score 1	Count	0	2	2	4
	Percentage within tumour budding pancytokeratin (score)	0.0	66.7	8.0	13.3
Score 2	Count	0	0	18	18
	Percentage within tumour budding pancytokeratin (score)	0.0	0.0	72.0	60.0
Total	Tumour budding score in H and E stained sections	2	3	25	30
	Percentage within tumour budding pancytokeratin (score)	100.0	100.0	100.0	100.0
Symmetric measures
	Value	Asymptotic SEa	Approximatetb	Approximate significant	P
Measure of agreement
κ	0.431	0.142	3.745	<0.001	0.001
Number of valid cases	30

^aNot assuming the null hypothesis, ^bUsing the asymptotic standard error assuming the null hypothesis. SE: Standard error