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Overexpression of miR-486 reduces cell proliferation. (A and B) Relative expression of miR-486 following transfection of H2052 and H28 cells with miR-486 mimic (up to 72 h). (C and D) Cell proliferation following miR-486 induction (10 nM) in H2052 and H28 cells, respectively. CTR, control; LIPO, Lipofectamine; miR-CTR, miRNA control. Each value of cell growth refers to its non-induced condition. Statistical significance is indicated vs. the control: *P<0.05; **P<0.01; ***P<0.001.
