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. 2021 Apr 28;47(6):117. doi: 10.3892/ijmm.2021.4950

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Copyright: © Pinelli et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Combined effects of transfection and CDDP treatment on PIM1 expression. (A) Relative expression of PIM1. Expression values refer to the control condition (miRNA control=1). (B) Western blot analysis of PIM1 protein following 24 h of transfection with miR-486 and/or treatment with CDDP in H2052 and H28 cells. Values refer to the control condition. Statistical significance is indicated vs. control, ^**P<0.01; ^***P<0.001; and vs. the separate treatments, ^#P<0.05. PIM1, Provirus integration site for Moloney murine leukaemia virus 1; CDDP, cisplatin.