Figure 2.

Effects of myocardial infarction (MI) on ischemic acute kidney injury. A–D: peak blood urea nitrogen (BUN; A), kidney injury molecule (Kim)-1 immunostaining (both low-magnification and high-magnification images included; B), weight loss (C), and mortality (D) following ischemia reperfusion (IR) in animals that had undergone either a sham or MI surgery 9 wk prior. Kim-1 immunostaining was performed on kidneys 24 h following IR. *P < 0.05 by unpaired t test. For sham and MI groups, respectively, n = 17 and n = 16 in A, n = 5 and n = 6 in B, n = 6 and n = 8 in C, and n = 9 and n = 8 in D.