Skip to main content
. 2021 Jan 7;12(4):448–471. doi: 10.1039/d0md00370k

Fig. 22. Improving efflux of DLK, MAP3K12 inhibitors via oxetane incorporation.89aMDCK-MDR1 permeability; AB = apical-to-basolateral; BA = basolateral-to-apical. bPiperidine pKa values were calculated using ACDLabs.90cTopological polar surface area.

Fig. 22