TABLE 1.
Univariate Analysis of Risk Factors Significantly Associated With Mortality in the Entire Cohort, With Coronavirus Disease 2019 Infection as an Underlying Risk Factor
| Risk Factor | Expired Patients | Alive Patients | p |
|---|---|---|---|
| n = 217 | n = 167 | ||
| Coronavirus disease 2019 infection, n (%) | 122 (56) | 70 (42) | 0.007 |
| Paralytic use, n (%) | 85 (39) | 29 (17) | < 0.001 |
| Vasopressor use, n (%) | 112 (52) | 68 (41) | 0.039 |
| Age, median (IQR) | 68 (60–76) | 62 (53–71) | < 0.001a |
| Lowest Pao2/Fio2, median (IQR) | 92 (74–115) | 99 (79–160) | 0.002b |
| Sequential Organ Failure Assessment score, median (IQR) | 11 (9–13) | 10 (8–13) | 0.003b |
| Pao2/Fio2 day 3, median (IQR) | 160.0 (100.0–209.0) | 177.5 (125.5–238.5) | 0.008b |
| PEEP day 3, median (IQR) | 12 (9–15) | 10 (8–14) | 0.027a |
| Pao2/Fio2 day 7, median (IQR) | 144 (91.5–187) | 176.0 (126.5–219) | < 0.001b |
| PEEP day 7, median (IQR) | 12 (8–16) | 8 (5–13) | < 0.001a |
IQR = interquartile range, PEEP = peak end-expiratory pressure.
Fisher exact test used for dichotomous variables, Student t test (a) or Mann-Whitney U test (b) for continuous variables.
Bolded p values indicate statistically significant values < 0.05.