Table 1.

Comparison of observation indexes of each group before treatment.

	NC (n = 40) (mean ± SD)	non-DPN(n = 44) (mean ± SD)	DPN (n = 83) (mean ± SD)	Value	Value
Age (yrs)	53.98 ± 5.50	54.07 ± 7.76	56.17 ± 6.28	2.252	.108
Gender (Male/Female)	22/18	24/20	44/41	0.697	.552
Course of disease (years)	/	5.33 ± 1.79	7.34 ± 1.99Δ	31.19	<.001
SBP (mm Hg)	127.98 ± 7.84	128.36 ± 9.17	129.82 ± 8.78	0.768	.465
DBP (mm Hg)	75.18 ± 6.64	76.43 ± 6.38	75.92 ± 7.99	0.314	.731
TC (mmol/L)	3.81 ± 1.50	3.65 ± 1.71	3.62 ± 1.61	1.447	.238
LDL-C (mmol/L)	2.05 ± 0.61	2.11 ± 0.53	2.16 ± 0.51	0.661	.573
TG (mmol/L)	1.20 ± 0.25	1.23 ± 0.23	1.29 ± 0.27	1.886	.155
sCr (umol/l)	71.93 ± 14.77	71.59 ± 15.53	71.88 ± 13.11	0.007	.993
BMI (kg/m2)	22.64 ± 1.99	24.33 ± 2.47#	24.68 ± 2.52#	10.198	<.001
FBG (mmol/)	5.41 ± 0.79	8.46 ± 1.47#	8.88 ± 1.64#	7.453	.001
2hPG (mmol/)	7.13 ± 1.28	11.41 ± 1.86#	11.64 ± 2.12#	8.097	<.001
FCP (ng/ml)	2.40 ± 0.41	2.31 ± 0.49	2.14 ± 0.44#Δ	5.195	.006
HbA1c (%)	5.17 ± 0.90	8.03 ± 1.04#	8.17 ± 1.16#	7.542	.001
apelin (ng/l)	348.36 ± 40.34	379.40 ± 38.34#	404.08 ± 50.87#Δ	20.617	<.001
TNF-α (pg/l)	10.13 ± 3.56	12.83 ± 2.96#	15.23 ± 3.89#Δ	27.847	<.001