Table 6.

ORs and 95% CIs for the MTHFR A1298C and URPL under different models.

Contrast	Group	No.	I2(%)	Model ∗	Pooled OR(95% CI)	Egger (P value)	P value †
CC + AC vs AA	Overall	21	54.5	REM	1.07 (0.90–1.26)	.06
	HWE: yes	17	43.1	FEM	0.99 (0.88–1.12)	.64
	Distribution: North	8	58.2	REM	1.24 (0.95–1.56)		.10
	Distribution: South	13	50.9	REM	0.97 (0.78–1.24)
CC vs AA + AC	Overall	21	0.0	FEM	1.55 (1.25–1.93)	.04
	HWE: yes	17	1.6	FEM	1.54 (1.21–1.97)	.08
	Distribution: North	8	9.6	FEM	1.63 (1.21–2.19)		.64
	Distribution: South	13	0.0	FEM	1.47 (1.06–1.93)
AC vs AA	Overall	21	56.5	REM	1.02 (0.85–1.21)	.75
	HWE: yes	17	39.3	FEM	0.92 (0.81–1.05)	.97
	Distribution: North	8	67.9	REM	1.17 (0.87–1.58)		.15
	Distribution: South	13	45.6	FEM	0.95 (0.82–1.11)
CC vs AA	Overall	21	0.0	FEM	1.53 (1.22–1.91)	.06
	HWE: yes	17	0.0	FEM	1.49 (1.16–1.91)	.10
	Distribution: North	8	0.0	FEM	1.57 (1.15–2.13)		.82
	Distribution: South	13	0.0	FEM	1.49 (1.07–2.07)
C vs A	Overall	21	52.7	REM	1.10 (0.97–1.26)	.29
	HWE: yes	17	49.9	FEM	1.07 (0.97–1.18)	.29
	Distribution: North	8	51.1	REM	1.22 (1.01–1.47)		.08
	Distribution: South	13	51.9	REM	1.02 (0.85–1.23)