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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Alzheimers Dement. 2020 Jul 27;17(1):7–17. doi: 10.1002/alz.12156

Figure 1. Dose by timepoint FDG PET SUVR by region of interest.

Figure 1.

The box and whiskers plots illustrate pre- and post-treatment SUVR values across 12 regions. The lower dose is shown in red, and the higher dose in blue. P values were determined using a linear mixed-model approach and reflect the significance of the primary effect of interest, the dose by time interaction. They were obtained by likelihood ratio tests of a full linear mixed model of OAA dose and study timepoint. This was tested against a reduced model without the interaction. P values between 0.045 and 0.049 are designated as <0.05; for other values the rounded decimal is indicated. The DMN values are a composite average of superior parietal cortex, precuneus, posterior cingulate cortex, and rostral anterior cingulate cortex measurements.