Table 4.
Logistic regression analyses of potential risk factors of mortality in severe COVID-19 patients
| Regression Coefficient | OR (Odds Ratio) | 95% CI | P value | |
|---|---|---|---|---|
| SOFA | 0.317 | 1.373 | 1.006–1.712 | 0.005 |
| Lowest leukocyte, ×109/L | 0.277 | 1.319 | 1.174–1.491 | < 0.001 |
| Lowest neutrophils, × 109/L | −0.011 | 0.989 | 0.976–1.001 | 0.080 |
| Lowest lymphocyte, ×109/L | 0.316 | 1.372 | 1.089–1.729 | 0.007 |
| Lowest prealbumin, g/L | −0.012 | 0.987 | 0.979–0.994 | 0.001 |
| Lowest albumin, g/L | 0.012 | 1.013 | 0.988–1.038 | 0.300 |
| Peak D-Dimer, mg/L | −0.001 | 0.998 | 0.991–1.005 | 0.632 |
| Peak aspartate aminotransferase, U/L | −0.004 | 0.995 | 0.992–0.997 | 0.000 |
| Peak blood urea nitrogen, mmol/L | 0.0004 | 1.000 | 0.989–1.011 | 0.931 |
| Peak serum creatinine, μg/L | 0.001 | 1.001 | 0.999–1.003 | 0.131 |
| Peak Interleukin −6, pg/mL | −0.000 | 0.999 | 0.998–1.000 | 0.880 |
| Peak C-reactive protein, mg/L | 0.006 | 1.006 | 1.000–1.012 | 0.036 |
| Peak lactate dehydrogenase, U/L | 0.003 | 1.003 | 1.001–1.005 | < 0.001 |
| Peak creatine kinase isoenzyme, U/L | 0.003 | 1.003 | 0.999–1.008 | 0.080 |
| Peak Troponin, pg/mL | 0.000 | 0.999 | 0.999–1.000 | 0.293 |
| Age, y | 0.057 | 1.059 | 1.030–1.088 | < 0.001 |
| Hscore 98–169 vs ≤98 | 1.393 | 4.028 | 1.553–10.444 | 0.004 |
| Hscore ≥169 vs ≤98 | 3.125 | 22.770 | 2.227–232.800 | 0.008 |
Abbreviations: SOFA Sequential Organ Failure Assessment
P value compare between survivor group vs nonsurvivor group, P < 0.05 means had significantly different